Mercedes-Benz CL-Class & S-Class (C216/W221; 2006-2014) fuses and relays

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In this article, we consider the third-generation Mercedes-Benz CL-Class (C216) and the fifth-generation Mercedes-Benz S-Class (W221), produced from 2006 to 2014. Here you will find fuse box diagrams of Mercedes-Benz CL550, CL600, CL63, CL65, S250, S280, S300, S320, S350, S400, S420, S450, S500, S550, S600, S63, S65 (2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013 and 2014), get information about the location of the fuse panels inside the car, and learn about the assignment of each fuse (fuse layout) and relay.

See other Mercedes-Benz CL-Class / S-Class:

Fuse Layout Mercedes-Benz CL-Class and S-Class 2006-2014


Cigar lighter (power outlet) fuses in the Mercedes-Benz CL-Class / S-Class are the fuses #117 (Rear cigar lighter), 134 (Luggage compartment socket), #140 (Rear cigar lighter / 115 V socket (from 2009)), #152 (115 V socket) in the Rear Fuse Box, and fuse #43 (Front cigar lighter) in the Engine Compartment Fuse Box.


Instrument Panel Fuse Box №1 (left)

Fuse box location

The fuse box is located on the left side of the instrument panel, behind the cover.The location of the fuses in the passenger compartment: Mercedes-Benz CL-Class / S-Class (C216/W221; 2006-2014)

Fuse box diagram

Instrument panel fuse box #1 diagram: Mercedes-Benz CL-Class / S-Class (2006-2014)

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Assignment of the fuses in the Instrument Panel Fuse Box №1
Fused functionAmp
92Left front seat control unit40
93Restraint systems control unit
USA version: Weight Sensing System (WSS) control unit
7.5
94from 2009: Multifunction camera5
95--
96Tire pressure monitor [RDK] control unit5
97W221: Audio/video controller control unit (rear entertainment system)7.5
98Rear entertainment system: DVD player (from 2009)7.5
99from 2009: COMAND display, SPLITVIEW display7.5
100from 2009: Media interface control unit5
101Rear entertainment system: Left rear display, Right rear display10
102Right front seat control unit40
103ESP control unit7.5
104Audio tuner control unit40
105--
106Japanese version: Electronic toll collection (ETC) control unit
Valid for South Korea as of 1.9.10: TV/tuner connector
Valid for navigation; from 2009: Navigation processor
1
107SDAR control unit (SIRIUS satellite radio) (W221 from 2009)
Digital radio: Digital Audio Broadcasting control unit
HD radio: High definition tuner control unit
5
108W221: Rear air conditioning control unit5
109W221: Rear blower intermediate connector15
110W221: Left rear multicontour backrest control unit, Right rear multicontour backrest control unit7.5
111Rear multicontour seat or rear entertainment system (model 221): RCP [HBF] control unit5
112W221; up to 2008: Left front door control unit, Right front door control unit
S 400 Hybrid: Front SAM control unit with fuse and relay module
5
113S 400 Hybrid: DC/DC converter control unit5

Instrument Panel Fuse Box №2 (right)

Fuse box location

It is located on the right side of the instrument panel, behind the cover.The location of the fuses in the passenger compartment: Mercedes-Benz CL-Class / S-Class (C216/W221; 2006-2014)

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Fuse box diagram

Instrument panel fuse box #2 diagram: Mercedes-Benz CL-Class / S-Class (2006-2014)

Assignment of the fuses in the Instrument Panel Fuse Box №2
Fused functionAmp
70C216: Right door control unit
W221: Right front door control unit
40
71Keyless Go control unit15
72S 400 Hybrid: Pyrotechnical separator7.5
73Japanese version: COMAND controller unit
TELE AID emergency call system (from 2009): Emergency call system control unit
5
74TLC [HDS] control unit (Remote trunk closing)30
75S 400 Hybrid: Battery management system control unit, Power electronics control unit10
76S 400 Hybrid: Vacuum pump relay (+)15
76Valid for model 221 with engine 642.8: AdBlue® relay supply-
77Advanced sound system: Sound amplifier (from 2009)50
78S 65 AMG with engine 275: Additional fan relay (from 2009)
Valid for model 221 with engine 642.8: AdBlue® relay supply (from 2009)
25
78S 400 Hybrid, CL 63 AMG with engine 157, 278: Charge air cooler circulation pump (from 2009)15
79Alarm signal horn with additional battery7.5
80C216: Left door control unit
W221: Left front door control unit
40
81C216: Rear control unit30
81W221: Left rear door control unit40
82C216: Rear control unit30
82W221: Left rear door control unit40
83Intelligent servo module for DIRECT SELECT30
84Advanced sound system: Digital sound processor (from 2009)20
85Valid for AMG: Illuminated door sill moldings (from 2009)10
86--
87--
88--
89--
90Stationary heater: STH heater unit (C216), STH or HB heater unit (W221)20
91Stationary heater: STH radio remote control receiver
S 400 Hybrid: Front SAM control unit with fuse and relay module
5

Rear Fuse Box

Fuse box location

It is located between the rear seats.
Swing down center armrest, open cover behind center armrest, pull cover 1 forward in direction of the arrow.Rear Fuse Box (location): Mercedes-Benz CL-Class / S-Class (2006-2014)

Fuse box diagram

Rear Fuse Box (diagram): Mercedes-Benz CL-Class / S-Class (2006-2014)

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Assignment of the fuses and relay in the Rear Fuse Box
Fused functionAmp
115Heated rear window50
116Valid for engine 157, 275, 278: Charge air cooler circulation pump
Valid for engine 156: Engine coolant circulation pump
S 400 Hybrid: Power electronics circulation pump 2
10
117Rear cigar lighter15
118Valid for engine 272, 273, 642: Fuel pump (up to 2008)
Valid for model 221 with engine 629, 642: Fuel pump (from 2009)
30
118S 400 Hybrid: Power electronics circulation pump 1
Valid for model 642.8 and engine 651 as of 1.6.11: Refrigerant compressor with magnetic
15
119Front central operating unit7.5
120--
121Audio tuner control unit10
122COMAND controller unit7.5
123W221: Right front reversible emergency tensioning retractor40
124W221: Left front reversible emergency tensioning retractor40
125up 31.5.09: Voice control system (VCS) control unit5
126Overhead control panel control unit25
127Lumbar pump (from 2009)
Multicontour seat pneumatic pump (Left/right front multicontour seats)
Pneumatic pump for dynamic seat control (Left and right dynamic multicontour seat)
30
128Valid for engine 275 (up to 2008): Fuel pump control unit
Valid for engine 156, 157, 272, 273, 275, 276, 278, 642 (from 2009): Fuel pump control unit
25
129up to 2008: Overhead control panel control unit (Power glass tilting/sliding roof)
from 2009: UPCI (Universal Portable Cell Phone Interface) control unit
25
130Electric parking brake controller unit30
131Rear window antenna amplifier module7.5
133Trailer recognition control unit
Reversing camera (as of 1.9.10)
15
134Luggage compartment socket15
135Park Assist; up 2008:
Radar sensors control unit (SGR)
Front short range radar sensor unit
Rear short range radar sensor unit
DISTRONIC PLUS up to 31.8.10 or Blind Spot Assist or Adaptive cruise control Plus Light: Radar sensors control unit (SGR) (from 2009)
PARKTRONIC or Exclusive parking assist: PTS control unit
7.5
136Valid for model 221 with engine 642.8: AdBlue® control unit7.5
137Reversing camera (as of 1.9.10)7.5
138Navigation processor (from 2009) (up to 31.8.10)
Emergency call system control unit (from 2009)
Japanese version: TV/tuner connector (from 2009)
5
139Rear backrest refrigerator box15
140Rear cigar lighter with ashtray illumination connector
115 V socket (from 2009)
15
141Reversing camera control unit5
142Parktronic system (PTS) control unit
Distronic Plus: Radar sensors control unit (SGR)
Valid as of 1.9.10 for DISTRONIC PLUS and Active Blind Spot Assist or Active Lane Keeping Assist: Video and radar sensor system control unit
7.5
143Rear seats control unit25
144Rear seats control unit25
145Trailer recognition control unit (up to 2008)
Trailer hitch socket (13-pin) (from 2009)
20
146Trailer recognition control unit25
147up to 2008: TLC [HDS] control unit (Remote trunk closing)30
148up to 2008: Universal Portable CTEL Interface (UPCI [UHI]) control unit7.5
148from 2009: Panoramic sliding sunroof circuit 30 connector sleeve25
149up to 2008: Voice control system (VCS [SBS]) control unit5
149from 2009: Panoramic sliding sunroof control module25
150TV combination tuner (analog/digital)
Japanese version: TV/tuner connector (from 2009)
7.5
151W221; up to 2008: Electric parking brake controller unit25
151W221; from 2009: Trailer recognition control unit20
152W221: Rear window antenna amplifier module7.5
152115 V socket: DC/AC converter control unit25
Relay
MTerminal 15 relay
NTerminal 15R relay
OPower outlet relay
PHeated rear window relay
QValid for engine 156, 157, 275, 278, 629: Circulation pump relay
S 400 Hybrid: Valid for model 221.095/195: Power electronics circulation pump relay 2
RCigar lighter relay
SFuel pump relay
Valid for engine 642.8 and engine 651 as of 1.6.11: Connected through the fuel pump: Refrigerant compressor magnetic clutch
S 400 Hybrid: Power electronics circulation pump relay 1

Engine Compartment Fuse Box

Fuse box location

The fuse box is located in the engine compartment (left-side on LHD, or right-side on RHD).The location of the fuses in the engine compartment: Mercedes-Benz CL-Class / S-Class (C216/W221; 2006-2014)

Fuse box diagram

Under-hood fuse box diagram: Mercedes-Benz CL-Class / S-Class (2006-2014)

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Assignment of the fuses and relay in the Engine Compartment Fuse Box
Fused functionAmp
20Valid for engine 629, 642, 651: CDI control unit
Valid for engines 156, 157, 272, 273, 275, 276, 278: ME-SFI [ME] control unit
10
21Valid for engines 156, 157, 272, 273, 275, 276, 278: Terminal 87 Ml i connector sleeve
Valid for model 221 with engine 629 and engine 642: CDI control unit Fuel pump relay
Valid for model 221 with engine 651: Quantity control valve
20
22Valid for engines 156, 157, 272, 273, 276, 278: Terminal 87 connector sleeve15
23up to 2008:
Terminal 87 connector sleeve
Valid for engine 275 (model 216):
Terminal 87 M1 i connector sleeve
Valid for engine 273 (model 216):
Terminal 87 M2e connector sleeve
Valid for engine 272, 273 (model 221):
Terminal 87M2i connector sleeve
Valid for engine 642:
Terminal 87 connector sleeve

from 2009:
Valid for engine 156, 157, 272, 273, 275, 276, 278:
Terminal 87 connector sleeve
Valid for model 221 with engine 629 and engine 642:
Terminal 87 connector sleeve
Valid for engine 156, 157, 272, 273, 276, 278:
Terminal 87M2e connector sleeve
Valid for engine 275:
Terminal 87 M2i connector sleeve
Valid for model 221 with engine 629 and engine 642:
Terminal 87 connector sleeve
Valid for model 221 with engine 651:
Rear SAM control unit with fuse and relay module
20
24Valid for engines 157, 272, 273, 276, 278: Terminal 87Mle connector sleeve
Valid for engine 642: CDI control unit
25
25Instrument cluster7.5
26Left front lamp unit10
27Right front lamp unit10
28Valid for engine 275: EGS control unit
Valid without engine 275: Fully integrated transmission control (VGS) control unit
7.5
29Rear SAM control unit with fuse and relay module5
30Valid for engine 629, 642, 651: CDI control unit
Valid for engines 156, 157, 272, 273, 275, 276, 278: ME-SFI [ME] control unit Fuel pump control unit
7.5
31S 400 Hybrid: Electric refrigerant compressor5
32Valid for model with ECO start/stop function: Transmission oil auxiliary pump control unit
S 400 Hybrid: Transmission oil auxiliary pump control unit
15
33Valid as of 1.9.10 without model S 400 Hybrid: ESP control unit
S 400 Hybrid: Battery management system control unit DC/DC converter control unit Power electronics control unit
5
34S 400 Hybrid: Regenerative braking system control unit5
35Electric parking brake controller unit5
36Data link connector (Pin 16)10
37For EIS control unit7.5
38Central gateway control unit7.5
39Instrument cluster7.5
40Upper control panel control unit7.5
41Slave wiper motor30
42Master wiper motor30
43Front cigar lighter with ashtray illumination15
44--
45S 400 Hybrid: Power electronics circulation pump 15
46W221 with Active Body Control (ABC), model 216: ABC control unit
W221 without Active Body Contro (ABC): AIRmatic with ADS control unit
15
47Front SAM control unit with fuse and relay module
Steering column up/down motor
15
48up to 2008: Front SAM control unit with fuse and relay module

from 2009: Steering column in/out motor
15
49Steering column module10
50AAC [KLA] control unit15
51up to 2008:  COMAND display 7.5
51from 2009:
COMAND display
SPLITVIEW display
5
52AW221:
Left fanfare horn
Right fanfare horn
15
52BW221, C216:
Left fanfare horn
Right fanfare horn
15
53--
54AC air recirculation unit40
55Valid for gasoline engine: Electric air pump60
56W221 without Active Body Contro (ABC): AIRmatic compressor unit40
57up 2008: Wiper park position heater40
57from 2009: Wiper park position heater30
60from 2009: Electrohydraulic power steering5
61C216; W221 - from 2009: Restraint systems control unit7.5
61W221; up to 2008: Restraint systems control unit10
62Night View Assist control unit5
63Valid for model 221 with engine 629 and engine 642 as of 1.9.08: Fuel filter condensation sensor with heating element15
64W221 as of 1.9.06: Driver NECK-PRO head restraint solenoid, Front passenger NECK-PRO head restraint solenoid7.5
64W221 as of '09: Driver NECK-PRO head restraint solenoid, Front passenger NECK-PRO head restraint solenoid10
65Valid as of 1.6.09: 12 Volt connector in glove box15
66DTR controller unit (Distronic or Distronic Plus)7.5
Relay
AAir pump relay
BAir suspension compressor relay
CTerminal 87 relay, engine
DTerminal 15 relay
ETerminal 87 relay, chassis
FFanfare horn relay
GTerminal 15R relay
HCircuit 50 relay, starter
JCircuit 15 relay, starter
KWiper park heater relay

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Engine Pre-Fuse Box

Engine Pre-Fuse Box: Mercedes-Benz CL-Class / S-Class (2006-2014)

Up to 2008

Fused functionAmp
1Starter400
2Not valid for engine 642: Alternator
Valid for engine 642: Alternator
150/200
3-150
4AAC with integrated control additional fan motor150
5Valid for engine 642: PTC heater booster200
6Front SAM control unit with fuse and relay module200
7ESP control unit40
8ESP control unit25
9Front SAM control unit with fuse and relay module20
10Vehicle power supply control unit7.5

From 2009

Fused functionAmp
3Rear SAM control unit with fuse and relay module150
4ECO start/stop function: ECO start/stop function relay
S 400 Hybrid: DC/DC converter control unit
Heated windshield: Heated windshield control unit
150
5Valid for model 221 (Electrical preinstallation for rental vehicle): Special vehicle multifunction control unit (SVMCU [MSS])125
5S 400 Hybrid: Vacuum pump40
6Right dashboard fuse box80
7Valid for model 221 with engine 629, 642, 651: PTC heater booster
Valid for model 221 (Electrical preinstallation for rental vehicle): Special vehicle multifunction control unit (SVMCU [MSS])
150
8Front SAM control unit with fuse and relay module80
9Left dashboard fuse box80
10Rear SAM control unit with fuse and relay module150

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Interior Pre-fuse Box

Up to 2008

Fused functionAmp
1Front prefuse box (via on-board electrical network line pyrofuse)
2Heated windshield control unit125
3Right instrument panel fuse box80
4Rear SAM control unit with fuse and relay module200
5Special vehicle multifunction control unit (SVMCU [MSS])100
6Rear SAM control unit with fuse and relay module150
7Front SAM control unit with fuse and relay module100
8Left instrument panel fuse box80
9Front SAM control unit with fuse and relay module5
10C216: Emergency call system control unit5

From 2009

Fused functionAmp
2Alternator400
3Electrohydraulic power steering
Valid for model 221 with engine 629, 642: Glow time output stage
150
4Interior prefuse box ( unfused)-
5AAC with integrated control additional fan motor100
6Front SAM control unit with fuse and relay module150
7ESP control unit
S 400 Hybrid: Regenerative braking system control unit
40
8ESP control unit
S 400 Hybrid: Regenerative braking system control unit
25
9Front SAM control unit with fuse and relay module25
10Spare-

AdBlue Fuse Block

Fused functionAmp
AAdBlue control unit7.5
BHeater circuit 120
CHeater circuit 220
DSpare-

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